Product Type: Inhibitor
CAS No.: 179324-69-7
MolecularFormula: C19H25BN4O4
Molecular Weight: 384,2
Source: Synthetic
Purity: >98%
Solubility: Soluble in 50 mg/ml DMSO, 35 mg/ml Ethanol
Appearance: White Powder
PubChem CID: 387447
Scientific Background: Potent and selective proteasome inhibitor (Ki=0.6 nM). Inhibits proliferation of a number of tumor cell lines (IC50=7 nM). Inhibits TNF synthesis and FGF-induced angiogenesis. Reversible. Cell permeable.
References: 1. Adams J., et al. (1999) Cancer Res. 59: 2615. 2. Williams S., et al. (2003) Mol. Cancer Ther. 2: 835.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.