Products from BPS Bioscience require a minimum order value above 400€
Applications: Great for screening small molecular inhibitors for drug discovery and HTS applications.
Description: The BRD4 (BD2) TR-FRET Assay Kit is designed to measure the inhibition of BRD4(BD2) binding to its substrate in a homogeneous 384 reaction format. This FRET-basedassay requires no time-consuming washing steps, making it especially suitable for highthroughput screening applications. The assay procedure is straightforward and simple; asample containing terbium-labeled donor, dye-labeled acceptor, BRD4, substrate, andan inhibitor is incubated for sixty minutes. Then, the fluorescence intensity is measuredusing a fluorescence reader.
Storage Stability: At least 12 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
Supplied As: Kit comes in a convenient format with purified BRD4 (BD2), ligands, Tb donor, dye-labeled acceptor, assay buffer and microtiter plate to perform 384 reactions.
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: Filippakopoulos, P., et al., Cell 2012; 149:214.
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