C14-A1

C14-A1
SKU
CAY40256-10
Packaging Unit
10 mg
Manufacturer
Cayman Chemical

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Formulation: A solution in ethanol

Formal Name: 1,1'-((5-(4-(2-((5-(bis(2-hydroxytetradecyl)amino)pentyl)(2-hydroxytetradecyl)amino)ethyl)piperazin-1-yl)pentyl)azanediyl)bis(tetradecan-2-ol)

Purity: ≥95%

Formula Markup: C86H177N5O5

Formula Weight: 1361,4

Shelf life (days): 730

Notes: C14-A1 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs).{72229} LNPs containing C14-A1 and encapsulating mRNA expressing forkhead box protein P3 (FOXP3) increase FOXP3 levels in primary human T cells. LNPs containing C14-A1 and encapsulating mRNA expressing FOXP3 also reduce the proliferation of primary human CD4+/CD8+ T cells, as well increase TGF-β1 and decrease IL-10 secretion from CD4+/CD8+ T cells.
More Information
SKU CAY40256-10
Manufacturer Cayman Chemical
Manufacturer SKU 40256-10
Package Unit 10 mg
Quantity Unit STK
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