C14-A1

Formulation: A solution in ethanol

Formal Name: 1,1'-((5-(4-(2-((5-(bis(2-hydroxytetradecyl)amino)pentyl)(2-hydroxytetradecyl)amino)ethyl)piperazin-1-yl)pentyl)azanediyl)bis(tetradecan-2-ol)

Purity: ≥95%

Formula Markup: C86H177N5O5

Formula Weight: 1361,4

Shelf life (days): 730

Notes: C14-A1 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs).{72229} LNPs containing C14-A1 and encapsulating mRNA expressing forkhead box protein P3 (FOXP3) increase FOXP3 levels in primary human T cells. LNPs containing C14-A1 and encapsulating mRNA expressing FOXP3 also reduce the proliferation of primary human CD4+/CD8+ T cells, as well increase TGF-β1 and decrease IL-10 secretion from CD4+/CD8+ T cells.

• SKU: CAY40256-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 40256-10
• Package Unit: 10 mg
• Quantity Unit: STK