Notes: C16 α-Glucosylceramide is a bioactive glycosphingolipid.{41488,41489} It is a precursor in the synthesis of C16 lactosylceramide (Item No. 24352) that is formed via metabolism of C16 ceramide (Item No. 10681) by glucosylceramide synthase.{41133} Inhalation of C16 glucosylceramide reduces lung colonization by P. aeruginosa and increases survival in a mouse model of cystic fibrosis.{41488} C16 Glucosylceramide levels are elevated in the plasma of Parkinson's disease patients with cognitive impairments.{41489} This product is fully synthetic and has no variations in the fatty acyl chain or sphingoid backbone.