C16, CAS 608512-97-6

PKR kinase inhibitor

Product Type: Inhibitor

CAS No.: 608512-97-6

MolecularFormula: C13H8N4OS

Molecular Weight: 268,3

Source: Synthetic

Purity: ≥98% (HPLC)

Solubility: Soluble in DMSO 12 mg/ml

Appearance: Solid

PubChem CID: 67016828

Scientific Background: C16 is a derivative of imidazolo-oxindole and inhibits RNA-dependent protein kinases (PKR). Its inhibition effect on PKR is ATP-binding site directed. C16 has been shown to specifically inhibit the apoptotic PKR/eIF2a signaling pathway.

References: 1. Couturier J., et al. (2010) J. Biol. Chem. 285(2): 1272–1282. 2. Jammi N.V., Whitby L.R., & Beal P.A. (2003) Biochem. Biophys.Res. Comm. 308(1):50–57.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-498-25MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-498-25MG
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK