Abbreviation: C5AR1
Target Synonym: C5AR1;C5A;C5AR;C5R1;CD88
Conjugation: Unconjugated
UNIProt ID: P21730
Background: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human C5AR1
Dilution: WB 1:500-1:2000,IHC 1:50-1:200