C9-200

Formulation: A solution in ethanol

Formal Name: 1,1'-((2-(4-(2-((2-(bis(2-hydroxynonyl)amino)ethyl)(2-hydroxynonyl)amino)ethyl)piperazin-1-yl)ethyl)azanediyl)bis(nonan-2-ol)

Purity: ≥95% (mixture of isomers)

Formula Markup: C55H115N5O5

Formula Weight: 926,5

Shelf life (days): 1095

Notes: C9-200 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs).{69788} LNPs containing C9-200 and encapsulating mRNA encoding erythropoietin (EPO) increase serum EPO levels in mice. LNPs containing C9-200 and encapsulating mRNA encoding the Cas9 nuclease and small-guide RNA (sgRNA) targeting transthyretin (TTR) induce 3-fold higher hepatic insertion and deletion (indel) formation than LNPs containing C12-200 (Item No. 36699) and encapsulating mRNA encoding Cas9 in mice.

• SKU: CAY40862-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 40862-1
• Package Unit: 1 mg
• Quantity Unit: STK