Clone Name: Calp3c/12A2
Application Note: WB: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 94
Specificity/Sensitivity: This antibody reacts with full-size calpain 3 (94 kD) plus an additional breakdown product at 60 kD.
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008]
Uniprot ID: P20807
Antigen Species: Human
Immunogen: Synthetic peptide containing amino acids 355-370 of the human calpain 3 sequence.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: calpain 3
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