Product Description: Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC50 of 25 nM against hP2X3 homotrimeric. Camlipixant shows potent anti-tussive effect and no taste alteration. Camlipixant can be used for the research of unexplained, refractory chronic cough[1].
Applications: COVID-19-immunoregulation
Formula: C23H24F2N4O4
References: [1]Garceau D, Chauret N. BLU-5937: A selective P2X3 antagonist with potent anti-tussive effect and no taste alteration. Pulm Pharmacol Ther. 2019 Jun;56:56-62.
CAS Number: 1621164-74-6
Molecular Weight: 458.46
Compound Purity: 99.94
Research Area: Inflammation/Immunology
Target: P2X Receptor