Formulation: A solid
Formal Name: N-(methyl-d3)-carbamic acid, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
Purity: ≥99% deuterated forms (d1-d3)
Formula Markup: C12H12D3NO3
Formula Weight: 224,3
Shelf life (days): 1460
CAS Number: 1007459-98-4
Notes: Carbofuran-d3 is intended for use as an internal standard for the quantification of carbofuran (Item No. 25635) by GC- or LC-MS. Carbofuran is a carbamate insecticide that inhibits acetylcholinesterase (AChE) in insects and mammals (Kas = 9.4, 30, and 210 µM for M. domestica brain, A. mellifera brain, and bovine erythrocyte AChE, respectively).{36349} It also inhibits AChE from rat and human erythrocytes with IC50 values of 40 and 25 nM, respectively.{37694} It is toxic to the housefly M. domestica (LD50 = 4.6 mg/kg) and fourth-instar larvae of the mosquito C. pipiens with an LC50 value of 0.054 ppm. Carbofuran is toxic to birds, rats (LD50 = 4-11 mg/kg), and other mammals, including dogs, sheep, and cattle, and is considered an environmental toxin.{36349,36347} Formulations containing carbofuran have been used in agriculture for the control of insects, nematodes, mites, and ticks.
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