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Clone Name: 4G19
Application Note: FACS: 1:100 - 1:800. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 41
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 500 μg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]
Uniprot ID: P51685
Antigen Species: Human
Immunogen: Human CCR8 transfected 293 cells
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: C-C motif chemokine receptor 8
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