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Encompassing Amino Acids: 32-360
Applications: Useful for studying protein binding and for screening small molecules and antibodies.
Description: Human secreted CD112, also known as Nectin-2, Herpes virus entry mediator B, HVEB, PVRL2, and PRR2, GenBank Accession No. NM_002856, a.a. 32-360 expressed in a HEK293 cell expression system, with C-terminal His and Avi™ tags, this protein is enzymatically biotinylated using Avi-tag™ technology. MW = 38.3 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Format: Aqueous buffer solution
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
Genbank: NM_002856
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal His-tag
Uniprot: Q92692
Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Biosafety Level: Not applicable (BSL-1)
References: 1. Bottino, C., et al., J. Exp. Med. 2003; 198(4): 557-567.
2. Pende, D., et al., Blood. 2005; 105(5): 2066-2073.
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