CD11c

CD11c, Monoclonal, IgG1, Host: Mouse, APC

Clone: BU-15.

Conjugate: APC.

Immunogen: Synovial fluid dendritic cells.

Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).

Description: This antobody reacts with the CD11c antigen. Human CD11c (alpha X integrin) complexes with CD18 (beta2 integrin) to form the complement receptor type 4 (CR4) heterodimer which binds to fibrinogen and is involved with monocyte/granulocyte adhesion during inflammatory responses. CD11c expression is restricted to leukocytes mainly of myeloid lineage with highest expression on macrophages.

This antibody reacts with the X chain of the CD11c/CD18 integrin heterodimer expressed on monocytes and weakly on granulocytes. The antibody stains macrophages in most types of tissues. In flow cytometry the antibody labels a T-cell subset and weakly a B-cell subset.

• SKU: IMS11CA3-100T
• Manufacturer: Immunostep
• Manufacturer SKU: 11CA3-100T
• Package Unit: 100 Tests
• Quantity Unit: PAK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: IgG1
• Human Gene ID: 3687
• Host: Mouse
• Conjugate: Conjugated, APC (Allophycocyanin)