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Encompassing Amino Acids: 24-187
Applications: Useful for studying protein binding and screening small molecular inhibitors
Description: Mouse secreted CD137, also known asTumor Necrosis Factor ReceptorSuperfamily member 9, TNFRSF9, and ILA,GenBank Accession No. NM_011612, a.a.24-187 fused at the C-terminus to the Fcportion of human IgG1, expressed in aHEK293 cell expression system. MW = 44kDa (monomer). This protein runs at ahigher MW by SDS-PAGE due toglycosylation.
Format: Aqueous buffer solution
Formulation: 8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.
Genbank: NM_011612
Storage Stability: At least 6 months at -80°C.
Tags: Fc fusion (hIgG1)
Uniprot: P20334
Warnings: Avoidfreeze/thaw cycles. Storing diluted protein isnot recommended, if necessary, includecarrier protein (BSA 0.1 - 0.5%).
Biosafety Level: Not applicable (BSL-1)
References: 1. Wilcox, R.A., et al., J. Clin. Invest. 2002; 109(5): 651-659.
2. Foell, J. et al., J. Clin. Invest. 2003; 111(10): 1505-1518.
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