CD146/MCAM Polyclonal Antibody, Rabbit

Abbreviation: CD146/MCAM

Target Synonym: MCAM; CD146; MUC18; cell surface glycoprotein MUC18

Conjugation: Unconjugated

UNIProt ID: P43121

Background: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human CD146/MCAM

Dilution: WB 1:500-1:2000

• SKU: ELSE-AB-92375-120
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-92375-120
• Green Labware: No
• Package Unit: 120 µl
• Quantity Unit: STK
• Reactivity: Human, Rat (Rattus)
• Clonality: Polyclonal
• Application: Western Blotting
• Isotype: IgG
• Host: Rabbit