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Encompassing Amino Acids: 22-229
Application: Useful for studying protein binding and for screening small molecules and antibodies.
Description: Human CD244, Fc fusion protein, also known as Natural Killer Cell Receptor 2B4. GenBank Accession No. NM_016382, a.a. 22-229 expressed in a HEK293 cell expression system. This protein is fused at the C-terminus to the Fc region of human IgG1 and is enzymatically biotinylated using Avi-tag™ technology. MW = 52 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Format: Aqueous buffer solution
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Genbank: NM_016382
Storage Stability: At least 6 months at -80°C. Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.
Tags: C-terminal Avi-tag™
Uniprot: Q9BZW8
Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Biosafety Level: Not applicable (BSL-1)
References: 1.Eissmann, P. et al., Blood. 2004; 105: 4722-4729.2.Watzl, C. et al., Journal of Immunology. 2000; 165(7): 3545-3548.
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