Clone Name: HCAM/2875R
Application Note: WB: 1-2 μg/ml. IHC-P: 0.25-0.5 μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 82
Specificity/Sensitivity: Its epitope is resistant to digestion by trypsin and chymotrypsin. This antibody selectively interferes with lymphocyte binding to lymph node, mucosal and synovial endothelium.
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.
Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Uniprot ID: P16070
Antigen Species: Human
Immunogen: Stimulated human leukocytes
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: CD44 molecule (Indian blood group)
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