Description: Recognizes a 180-185 kDa protein, identified as isoform of leukocyte common antigen (CD45RO) (4th Leucocyte Typing Workshop: Code No. N31). The epitope recognized by this antibody is sensitive to neuraminidase digestion. This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Conjugate: Purified, BSA-free
Concentration: 1 mg/mL
Storage buffer: PBS, no BSA, no azide
Product Origin: Animal - Mus musculus (mouse)
Clone: UCHL-1
Entrez Gene ID: 5788
Immunogen: Cultured human T-cells from an IL-2-dependent T-cell line (CA1) (UCHL-1); Recombinant human CD45RO protein (T200/797)
Expected AB Applications: Functional studies (published for clone)/IP (published for clone)/WB (published for clone)
Verified AB Applications: Flow (surface) (verified)/IF (verified)/IHC (FFPE) (verified)
Z-Antibody Applications: Functional studies (published)/Flow, surface (verified)/IF (verified)/IHC, FFPE (verified)/IP (published)/WB (published)
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