Clone: L17F12.
Conjugate: FITC.
Immunogen: Human T-acute lymphoblastic leukemia (ALL) cells.
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).
Description: This antibody reacts with the CD5-antigen (T1-antigen), which is expressed on human T lymphocytes. The nonoclonal antibody reacts with 90% of human peripheral T lymphocytes, medullary thymocytes as well as with lymphocytes of patients with chronic B-cell derived leukaemia. It is also expressed on a small subpopulation of normal B cells in a range of neoplastic B cells. The antibody does not react with, monocytes, granulocytes and platelets.
This antibody identifies a 67 kDa lymphocyte surface antigen belonging to the CD5 cluster on peripheral blood T lymphocytes, 70% of thymocytes and a limited number of malignancies of T cell origin. The CD5 antigen is expressed on the majority of malignant B CLL, T CLL and T ALL cells and a proportion of B lymphoma cells.
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