Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Conjugate: Purified, BSA-free
Concentration: 1 mg/mL
Storage buffer: PBS, no BSA, no azide
Product Origin: Animal - Mus musculus (mouse)
Clone: SPV-L14
Entrez Gene ID: 923
Immunogen: CD8 cytotoxic T-cell clone
Expected AB Applications: Flow, surface (published for clone)/Functional studies (published for clone)/IF (published for clone)
Verified AB Applications: Flow (verified)/IF (verified)
Z-Antibody Applications: Flow (verified)/Flow, surface (published)/Functional studies (published)/IF (published)/IF (verified)
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