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Clone Name: MSVA-465R
Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.
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Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 77
Positive Control: Colon: An at least moderate cytoplasmic CEA staining should be seen in the vast majority of columnar epithelial cells.
Negative Control: Colon: CEA staining should not be seen in stromal cells or smooth muscle.
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format), 0.05% sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Uniprot ID: P06731
Antigen Species: Human
Immunogen: Recombinant full-length human CEA protein
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: carcinoembryonic antigen related cell adhesion molecule 5
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