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Encompassing Amino Acids: 39-193
Applications: Useful for studying protein binding and for screening small molecules and antibodies.
Description: Human CD70, also known as CD70 antigen, Tumor Necrosis Factor Ligand Superfamily Member 7, TNFSF7, CD27 Ligand, Ki-24 antigen, CD27-L, and CD27LG, GenBank Accession No. NM_001252, a.a. 39-193 with N-terminal His-tag, expressed in a HEK293 cell expression system. MW = 19.7 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Endotoxin Level: <1 EU/µg
Format: Aqueous buffer solution
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Genbank: NM_001252
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal, His-tag
Uniprot: P32970
Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Biosafety Level: Not applicable (BSL-1)
References: 1. Arens, R. et al., Immunity. 2001; 15(5): 801-812.
2. Law, C.L. et al., Canc. Res. 2006; 66: 2328-2337.
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