Application Note: WB: 0.25-0.5 μg/mL. IHC-P: 2-5 μg/mL. FACS: 1-3 μg/1x10⁶ cells. ELISA: 0.1-0.5 μg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 88
Form: Liquid
Buffer (with preservative): 4mg Trehalose, 0.9mg NaCl, 0.2 mg Na₂HPO₄, no preservatives.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
Uniprot ID: P55287
Antigen Species: Human
Immunogen: E.coli-derived human OB Cadherin/CDH11 recombinant protein (Position: K371-S796).
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: cadherin 11
English
Deutsch
