Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2385 U34070.1 592-2976
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CEBPA
Key Reference: Singh,S.M., (2008) Biochem. Biophys. Res. Commun. 369 (2), 692-694
Molecular Weight: 37kDa
Peptide Sequence: Synthetic peptide located within the following region:
RRERNNIAVRKSRDKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: CCAAT/enhancer-binding protein alpha
Protein Size: 358
Purification: Affinity Purified
English
Deutsch
