Formulation: A solid
Formal Name: 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt
Purity: ≥98%
Formula Markup: C13H12N5O5S2 • Na
Formula Weight: 405,4
Shelf life (days): 1460
CAS Number: 68401-82-1
Notes: Ceftizoxime is a cephalosporin antibiotic.{62850} Ceftizoxime is active against clinical isolates of the Gram-positive bacteria S. aureus, S. pyogenes, and S. epidermidis (IC50s = 1.56, ≤0.025, and 0.78 µg/ml, respectively), as well as clinical isolates of the Gram-negative bacteria E. coli, K. pneumoniae, and P. mirabilis (IC50s = 0.1, ≤0.025, and ≤0.025 µg/ml, respectively). It is protective against S. aureus, E. coli, P. mirabilis, or P. vulgaris infection in mice (ED50s = 4.03, 0.02, 0.255, and 0.038 mg/kg, respectively).{62851} Formulations containing ceftizoxime have been used in the treatment of a variety of bacterial infections.
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