eGFP/Firefly Luciferase MM.1S Cell Line

Products from BPS Bioscience require a minimum order value above 400€

Applications: Use as a control for killing assaysSuitable as a B-cell target for CAR-T or CAR-NK cells for optimizing CAR design

Background: MM.1S are multiple myeloma human B lymphoblasts. The parent cell line MM.1 was established from the peripheral blood of a multiple myeloma patient who had become resistant to steroid-based therapy. MM.1S cells are sensitive to dexamethasone.The cells were infected with an integrating Firefly luciferase-eGFP lentivirus (BPS Bioscience #79980-G) and cloned by limited dilution to get a monoclonal population. The cells stably express both the Firefly luciferase and enhanced GFP genes, making these cells an excellent tool to measure specific killing by CAR-T or NK cells.

Description: Recombinant stable MM.1S cell line constitutively expressing a firefly luciferase and enhanced GFP (eGFP) cassette  driven by a CMV promoter.

Host Cell Line: MM.1S

Mycoplasma Testing: The cell line has been screened to confirm the absence of Mycoplasma species.

Storage Stability: Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.

Supplied As: Each vial contains 2 x 106 cells in 1 ml of cell freezing medium (BPS Bioscience, #79796)

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: BSL-1

• SKU: BPS78376
• Manufacturer: BPS Bioscience
• Manufacturer SKU: 78376
• Package Unit: 2 vials
• Quantity Unit: PAK
• Host: Human