FcGR3B (CD16B) CHO Cell Line

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Applications: Screen antibodies against human CD16B or examine the function of CD16B in a cellular context.

Background: The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation.

Description: Recombinant clonal CHO cell line stably expressing full length human CD16B (also known as FCGR3B, FcγRIIIb, ref. seq. NM_000570) under the control of the CMV promoter.  The surface expression of CD16B was validated by flow cytometry.

Host Cell Line: CHO

Mycoplasma Testing: The cell line has been screened to confirm the absence of Mycoplasma species.

Storage Stability: Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long-term storage. 

Supplied As: Each vial contains 2 x 10⁶ cells in 1 ml of cell freezing medium (BPS Bioscience #79796)

Uniprot: O75015

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: BSL-1

• SKU: BPS78333
• Manufacturer: BPS Bioscience
• Manufacturer SKU: 78333
• Package Unit: 2 vials
• Quantity Unit: PAK
• Host: Hamster