Kategorie: Cytokines
Formulation: lyophilized
Storage: -20°C
Weight: 12219 D
Purity: >98%
Description: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 111 amino acids. CCL21 is expressed predominantly in the lymph nodes and, in contrast to other CC chemokines, is chemotactic for lymphocytes.