GRO-beta/MIP-2 (CXCL2), His-Tag, human recombinant (rHuGROb-His)

GRO-beta/MIP-2 (CXCL2), His-Tag, human recombinant (rHuGROb-His)
SKU
BOL97344.10
Packaging Unit
10 µg
Manufacturer
Biomol

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Kategorie: Cytokines

Formulation: purified

Storage: -20°C

Weight: 10100 D

Description: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. (www.uniprot.org) Recombinant human GRO-Beta produced in E.coli is a single, non-glycosylated, polypeptide chain containing 94 amino acids and having a molecular mass of 10.1 kDa. The GRO-b is fused to 20 amino acid His Tag at N-terminus. Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1. This chemokine is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. The gene for CXCL2 is located on human chromosome 4 in a cluster of other CXC chemokines. CXCL2 mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2.
More Information
SKU BOL97344.10
Manufacturer Biomol
Manufacturer SKU 97344.10
Package Unit 10 µg
Quantity Unit STK
Reactivity Human
Host Escherichia Coli
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