IL-15

Product Description: Interleukin-15 (IL-15) is a widely expressed proinflammatory cytokine that is structurally and functionally related to interleukin-2 (IL-2). IL-15 signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. IL-15 regulates the activation of T cells, neutrophils, and macrophages, and is a stimulatory cytokine promoting dendritic cell function. IL-15 expression is dysregulated in chronic inflammatory disorders, including rheumatoid arthritis, psoriasis, and pulmonary inflammatory diseases. Human IL-15 shows activity on mouse cells.

Growth Factor AA Sequence: MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS

• SKU: CGSGFH86-500
• Manufacturer: Cell Guidance Systems
• Manufacturer SKU: GFH86-500
• Package Unit: 500 μg
• Quantity Unit: STK
• Reactivity: Human