Interferon Gamma-Inducible protein 30, His tag, human recombinant (rHuIFI30-His)

Kategorie: Cytokines

Formulation: solution

Storage: -20°C

Weight: 22500 D

Purity: >90%

Description: IFI30 human recombinant produced in E. coli is a single polypeptide chain containing 199 amino acids (58-232) and having a molecular mass of 22.5 kDa. IFI30 is fused to a 24 amino acid His-tag at N-terminus. Gamma-interferon-inducible lysosomal thiol reductase (IFI30), is a part of the GILT family. IFI30 is a lysosomal thiol reductase which at low pH is capable of decreasing protein's disulfide bonds. IFI30 is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. Also, IFI30 plays an important role in MHC class II-restricted antigen processing. IFI30 facilitates the generation of MHC class II-restricted epitopes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds and also facilitates MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or cross-presentation.

• SKU: BOL97629.10
• Manufacturer: Biomol
• Manufacturer SKU: 97629.10
• Green Labware: No
• Package Unit: 10 µg
• Quantity Unit: STK
• Reactivity: Human
• Human Gene ID: 10437
• Host: Escherichia Coli