Description: Induces stromal cells to produce proinflammatory and hematopoietic cytokines (By similarity). (www.uniprot.org) Produced in E.coli. Homodimeric, non-glycosylated polypeptide chain containing 266 amino acids. The ED50 as determined by the dose-dependant secretion of IL-6 by NIH 3T3 cells was found to be 1.0-10.0 ng/mL.