Macrophage Inflammatory Protein-1 alpha (CCL3), rat recombinant (rrMIP-1a)

Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Weight: 7853 D

Purity: >95%

Description: Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 69 amino acids. CCL3 activates human granulocytes (neutrophils, eosinophils and basophils) which can lead to acute neutrophilic inflammation.

• SKU: BOL94880.1
• Manufacturer: Biomol
• Manufacturer SKU: 94880.1
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Rat (Rattus)
• Host: Escherichia Coli