Osteoprotegerin, Yeast, human recombinant (rHuOPG)

Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Weight: 46500 D

Purity: >90%

Description: Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis. (www.uniprot.org) Produced in yeast, containing 412 amino acid residues, including 180 residues from mature OPG (amino acids 22-201) and 232 residues from the Fc protein of human IgG1.

• SKU: BOL94902.1
• Manufacturer: Biomol
• Manufacturer SKU: 94902.1
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Host: Other