Kategorie: Cytokines
Formulation: sterile liquid
Storage: -20°C
Purity: >95%
Description: Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated polypeptide chain containing 211 amino acids (114-281)