Tumor Necrosis Factor alpha, rat recombinant (rrTNF-a)

Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Weight: 17339 D

Purity: >97%

Description: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated polypeptide chain containing 157 amino acids. The ED50 as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D is < 0.05ng/ml.

• SKU: BOL87356.1
• Manufacturer: Biomol
• Manufacturer SKU: 87356.1
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Rat (Rattus)
• Host: Escherichia Coli