Vascular Endothelial Growth Factor-121, human recombinant (rHuVEGF-121)

Kategorie: Cytokines

Storage: -20°C

Weight: 28423 D

Description: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in E.coli. Homodimer, polypeptide chain containing 2 x 121 amino acids.

• SKU: BOL52625.2
• Manufacturer: Biomol
• Manufacturer SKU: 52625.2
• Package Unit: 2 µg
• Quantity Unit: STK
• Reactivity: Human
• Host: Escherichia Coli