Stem cells possess the unique ability to differentiate into multiple lineages of cells including chondrocytes. Lonza’s hMSC Chondrogenic Differentiation BulletKit Medium is a serum containing medium designed to induce chondrogenic differentiation, with the addition of TGF-β3, of human bone marrow derived mesenchymal stem cells into mature, functionally active chondrocytes in as few as 14 days. Differentiation can then be validated by a variety of methods including staining with alcian blue or safranin. Partial List of Cells Differentiated with hMSC Chondrogenic Differentiation BulletKit Medium*: Human bone marrow derived stem cells Human umbilical cord blood derived stem cells Human umbilical cord matrix derived stem cells C57BL/6 mice bone marrow derived stem cells human adipose derived stem cells Human hamstring tendon derived stem cells The hMSC Chondrogenic Differentiation BulletKit Medium, with the addition of TGF-β3 (sold separately) provides a differentiation medium guaranteed to induce chondrogenic differentiation of human bone marrow derived mesenchymal stem cells into mature, functionally active chondrocytes; Each bottle of the hMSC Chondrogenic Differentiation BulletKit Medium contains enough differentiation medium to fully differentiate at least 2 million human bone marrow derived mesenchymal stem cells [approximately 4 complete 24-well plates] into mature, functionally active chondrocytes.
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