Abbreviation: CENPJ
Target Synonym: CENPJ;BM032;CENP-J;CPAP;LAP;LIP1;MCPH6;SASS4;SCKL4;Sas-4
Conjugation: Unconjugated
UNIProt ID: Q9HC77
Background: This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. Alternatively spliced transcript variants have been found for this gene.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human CENPJ
Dilution: WB 1:500-1:2000
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