CHIR99021, CAS 252917-06-9

GSK3β kinase inhibitor

Product Type: Inhibitor

CAS No.: 252917-06-9

MolecularFormula: C22H18Cl2N8

Molecular Weight: 465,3

Source: Synthetic

Purity: ≥98% (HPLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (25mg/mL, warm)

Appearance: White to light brown solid

PubChem CID: 9956119

Scientific Background: CHIR99021 is a potent and highly selective glycogen synthase kinase 3 (GSK-3) inhibitor. It also promotes self-renewal of mouse and human ESC due to β-catenin and c-Myc protein level stabilization.

References: 1. Ye S., et al. (2012) PloS One 7(4): e35892.2. Ring D. B., et al. (2003). Diabetes. 52(3): 588–595.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-437-1MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-437-1MG
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK