Formulation: A solid
Formal Name: L-lysine, 6-[[[(3β)-cholest-5-en-3-yloxy]carbonyl]oxy]hexyl ester, 2,2,2-trifluoroacetate
Purity: ≥95%
Formula Markup: C40H72N2O5 • 2CF3COO
Formula Weight: 887,1
Shelf life (days): 730
CAS Number: 1356250-80-0
Notes: Cho-es-Lys is a cationic cholesterol derivative composed of cholesterol (Item No. 9003100) conjugated to an L-lysine head group containing two primary amines (pKas = 10.48 and 9.46) via a hexanediol linker.{65677,65678} It has been used for transfection of Cy3-pDNA in COS-7 cells. Cho-es-Lys nanocomplexes containing luciferase siRNA reduce luciferase levels in vitro.{65678}