Abbreviation: CHRM1
Target Synonym: CHRM1;HM1;M1;M1R
Conjugation: Unconjugated
UNIProt ID: P11229
Background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human CHRM1
Dilution: WB 1:500-1:2000,IHC 1:500-1:2000,IF 1:50-1:200
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