CK7, CAS 507487-89-0

Formulation: A solid

Formal Name: 4-(2-amino-4-methyl-5-thiazolyl)-N-(3-nitrophenyl)-2-pyrimidinamine

Purity: ≥95%

Formula Markup: C14H12N6O2S

Formula Weight: 328,4

Shelf life (days): 1460

CAS Number: 507487-89-0

Notes: CK7 is an inhibitor of cyclin-dependent kinase 2 (Cdk2) and Cdk9 (Kis = 2 and 4 nM, respectively).{69582} It is selective for Cdk2 and Cdk9 over Cdk1, Cdk4, and Cdk7 (Kis = 80, 53, and 70 nM, respectively), as well as 10 additional kinases (Kis = >1,000 nM for all). CK7 is cytotoxic to A2780 ovarian and MES-SA uterine cancer cells (IC50s = 41 and 140 nM, respectively).{69583}

• SKU: CAY39153-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 39153-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK