Formulation: A solid
Formal Name: (3R)-3,4-dihydro-6,8-dihydroxy-3-[[(2R,6S)-tetrahydro-6-methyl-2H-pyran-2-yl]methyl]-1H-2-benzopyran-1-one
Purity: ≥70%
Formula Markup: C16H20O5
Formula Weight: 292,3
Shelf life (days): 1460
CAS Number: 35818-31-6
Notes: Cladosporin is a microbial metabolite originally isolated from C. cladosporiodes that has diverse biological activities.{66747,66746,66748} It selectively inhibits P. falciparum lysyl-tRNA ligase over human lysyl-tRNA ligase (IC50s = 0.061 and >20 µM, respectively).{66747} Cladosporin inhibits the replication of eight strains of Plasmodium with IC50 values ranging from 45.4 to 89.6 nM and decreases P. falciparum protein synthesis by 75% at 610 nM. It is active against the bacteria M. flavus (MIC = 40 µg/ml) and inhibits spore germination by the plant pathogenic fungi P. viridicatum when used at a concentration of 5 µg/ml.{66746} Cladosporin (30 µM) inhibits the growth of the plant pathogenic fungi C. acutatum, C. fragariae, C. gloeosporioides, and P. viticola.{66748}
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