Abbreviation: CNOT7
Target Synonym: CNOT7;CAF-1;CAF1;Caf1a;hCAF-1
Conjugation: Unconjugated
UNIProt ID: Q9UIV1
Background: The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human CNOT7
Dilution: WB 1:200-1:2000,IHC 1:50-1:200
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