Cocktail: Mouse anti-UPIII (AU1) & Rabbit anti-UP II (Polyclonal)

Immunogen: UPII: Peptide-KLH conjugate. UPIII: Raised in mouse using AUM preparation from bovine urinary bladder as the immunogen.

Concentration: lot specific

Storage buffer: Tissue culture supernatant with sodium azide

Additional info: Uroplakins (UPs) are a family of transmembrane proteins (UPs Ia, Ib, II and III) that are specific differentiation products of urothelial cells. In non-neoplastic mammalian urothelium, UPs are expressed in the luminal surface plasmalemma of superficial (umbrella) cells, Uroplakin II/III cocktail is specific for tumors of urothelial origin and, when used in combination with other markers, can aid in the diagnosis of primary and metastatic tumors.

References: Moll et al. Am J Pathol 1995;147:1383-1397/Olsburgh et al. J Pathol 2003;199:41-49/Parket et al. 2003;27:1-10

• SKU: SANMON9991
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON9991
• Package Unit: 1 ml
• Quantity Unit: STK
• Reactivity: Human
• Application: Immunohistochemistry (paraffin)
• Host: Mouse
• Conjugate: Unconjugated