Conjugation: Biotin
Description of Target: Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2. Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2 (Ungar et al., 2002 [PubMed 11980916]).[supplied by OMIM].
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human COG2
Key Reference: Sohda,M., (2007) Traffic 8 (3), 270-284
Molecular Weight: 83kDa
Peptide Sequence: Synthetic peptide located within the following region:
KRVQLEELRDDLELYYKLLKTAMVELINKDYADFVNLSTNLVGMDKALNQProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Conserved oligomeric Golgi complex subunit 2
Protein Size: 738
Purification: Affinity Purified
Subunit: 2
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