CP681301, CAS 865317-32-4

Product Description: CP681301 is a potent CDK5 inhibitor. CP681301 shows antiproliferative activity. CP681301 decreases the expression of CD133, OLIG2, SOX2, KI67, pCDK5 protein level in GSCs (Glioma stem cells). CP681301 reduces self-renewal in mouse glioma xenografts. CP681301 shows anti-tumor activity in Drosophila[1].

Applications: Cancer-Kinase/protease

Formula: C17H22N4O

References: [1]Mukherjee S, et al. CDK5 Inhibition Resolves PKA/cAMP-Independent Activation of CREB1 Signaling in Glioma Stem Cells. Cell Rep. 2018 May 8;23(6):1651-1664.

CAS Number: 865317-32-4

Molecular Weight: 298.38

Compound Purity: 99.18

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL

Target: CDK;DNA/RNA Synthesis

• SKU: MEXHY-150082-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-150082-5
• Package Unit: 5 mg
• Quantity Unit: STK