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Encompassing Amino Acids: 1081-1197
Applications: Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.
Description: Human bromodomain CREB binding protein (CREBBP), also known as CBP, RSTS and KAT3A, GenBank Accession No. NM_004380, a.a. 1081- 1197 corresponding to single bromodomain, with N-terminal His-tag, MW=14.9 kDa, expressed in an E. coli expression system.
Format: Aqueous buffer solution
Formulation: 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, and 10% glycerol
Genbank: NM_004380
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal His-tag
Uniprot: Q92793
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Panagopoulos, I., et al., Hum Mol Genet. 2001 Feb 15;10(4): 395-404.
2. Huang, W.C., et al., Mol Cell. 2007 Apr 13; 26(1):75-87.
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