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Clone Name: HL2674
Light Chain: Kappa
Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 40
Specificity/Sensitivity: This antibody was raised against human CXCR1 Extracellular domain.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008]
Uniprot ID: P25024
Antigen Species: Human
Immunogen: Synthetic peptide encompassing a sequence within the Extracellular domain of human CXCR1. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: C-X-C motif chemokine receptor 1
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